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Meng Zhang Selected Research

Small Interfering RNA (siRNA)

1/2022ADAM17 knockdown mitigates while ADAM17 overexpression aggravates cardiac fibrosis and dysfunction via regulating ACE2 shedding and myofibroblast transformation.
12/2021Epithelial exosomal contactin-1 promotes monocyte-derived dendritic cell-dominant T-cell responses in asthma.
5/2021Doxorubicin and PD-L1 siRNA co-delivery with stem cell membrane-coated polydopamine nanoparticles for the targeted chemoimmunotherapy of PCa bone metastases.
1/2021SHP-1 suppresses endotoxin-induced uveitis by inhibiting the TAK1/JNK pathway.
11/2020Enhanced antitumor effects of follicle-stimulating hormone receptor-mediated hexokinase-2 depletion on ovarian cancer mediated by a shift in glucose metabolism.
1/2020PDCD4 deficiency ameliorates left ventricular remodeling and insulin resistance in a rat model of type 2 diabetic cardiomyopathy.
1/2019Long non-coding RNA H19 promotes tumorigenesis of ovarian cancer by sponging miR-675.
11/2018Transcriptional control of the MUC16 promoter facilitates follicle-stimulating hormone peptide-conjugated shRNA nanoparticle-mediated inhibition of ovarian carcinoma in vivo.
11/2018Follicle-stimulating hormone peptide-conjugated nanoparticles for targeted shRNA delivery lead to effective gro-α silencing and antitumor activity against ovarian cancer.
1/2018Targeted-gene silencing of BRAF to interrupt BRAF/MEK/ERK pathway synergized photothermal therapeutics for melanoma using a novel FA-GNR-siBRAF nanosystem.
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Meng Zhang Research Topics

Disease

367Neoplasms (Cancer)
04/2024 - 06/2003
101Inflammation (Inflammations)
05/2024 - 09/2007
56Infections
04/2024 - 05/2007
45Neoplasm Metastasis (Metastasis)
02/2024 - 01/2005
42Colorectal Neoplasms (Colorectal Cancer)
01/2024 - 01/2005
38Prostatic Neoplasms (Prostate Cancer)
02/2024 - 06/2012
35Fibrosis (Cirrhosis)
03/2024 - 05/2011
35Carcinogenesis
01/2024 - 06/2003
33Stroke (Strokes)
11/2024 - 01/2006
33Hypertension (High Blood Pressure)
05/2024 - 06/2007
33Hepatocellular Carcinoma (Hepatoma)
01/2024 - 06/2003
29Breast Neoplasms (Breast Cancer)
03/2024 - 01/2013
29Hypoxia (Hypoxemia)
08/2023 - 09/2005
27Atherosclerosis
11/2024 - 06/2009
27Cardiovascular Diseases (Cardiovascular Disease)
05/2024 - 05/2009
26Ischemic Stroke
10/2023 - 01/2006
25COVID-19
11/2023 - 08/2020
24Pain (Aches)
03/2024 - 01/2016
24Stomach Neoplasms (Stomach Cancer)
11/2023 - 05/2007
23Colonic Neoplasms (Colon Cancer)
11/2023 - 09/2012
22Lung Neoplasms (Lung Cancer)
04/2024 - 10/2007
22Carcinoma (Carcinomatosis)
01/2024 - 06/2005
22Obesity
01/2024 - 05/2009
21Wounds and Injuries (Trauma)
05/2024 - 01/2013
20Renal Cell Carcinoma (Grawitz Tumor)
11/2023 - 03/2015
19Cognitive Dysfunction
05/2024 - 07/2010
19Myocardial Infarction
03/2024 - 01/2019
18Type 2 Diabetes Mellitus (MODY)
05/2024 - 09/2011
18Body Weight (Weight, Body)
04/2024 - 09/2012
18Sepsis (Septicemia)
03/2024 - 07/2008
18Alzheimer Disease (Alzheimer's Disease)
01/2024 - 07/2010
17Reperfusion Injury
03/2024 - 10/2003
17Ovarian Neoplasms (Ovarian Cancer)
02/2024 - 05/2013
17Hemorrhage
01/2024 - 12/2012
16Uterine Cervical Neoplasms (Cancer of the Cervix)
03/2024 - 02/2017
16Leukemia
02/2024 - 05/2004
16Glioma (Gliomas)
07/2023 - 06/2012
16Chronic Obstructive Pulmonary Disease (COPD)
05/2023 - 09/2011
16Brain Ischemia (Cerebral Ischemia)
10/2022 - 10/2003
15Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2024 - 02/2013
15Ischemia
12/2023 - 10/2003
15Adenocarcinoma
09/2023 - 09/2008
13Myocardial Ischemia (Ischemic Heart Diseases)
03/2024 - 06/2011
13Asthma (Bronchial Asthma)
02/2024 - 01/2015
12Necrosis
03/2024 - 03/2007
12Atherosclerotic Plaque (Atheroma)
02/2024 - 10/2016
12Osteosarcoma (Osteogenic Sarcoma)
01/2024 - 01/2002
12Osteoarthritis
01/2024 - 01/2016
12Heart Failure
01/2024 - 06/2011
12Rheumatoid Arthritis
01/2024 - 09/2015
11Prostatitis
01/2024 - 02/2020
11Urinary Bladder Neoplasms (Bladder Cancer)
12/2023 - 08/2015
10Pancreatic Neoplasms (Pancreatic Cancer)
01/2024 - 08/2005

Drug/Important Bio-Agent (IBA)

141Proteins (Proteins, Gene)FDA Link
03/2024 - 05/2005
90Biomarkers (Surrogate Marker)IBA
02/2024 - 05/2007
46CytokinesIBA
03/2024 - 08/2005
42Messenger RNA (mRNA)IBA
12/2023 - 06/2003
35MicroRNAs (MicroRNA)IBA
03/2024 - 12/2014
34RNA (Ribonucleic Acid)IBA
03/2024 - 01/2006
30Glucose (Dextrose)FDA LinkGeneric
05/2024 - 09/2011
30LipidsIBA
04/2024 - 11/2011
27Long Noncoding RNAIBA
02/2024 - 01/2015
25Therapeutic UsesIBA
05/2024 - 08/2005
24Reactive Oxygen Species (Oxygen Radicals)IBA
03/2024 - 06/2007
22EnzymesIBA
01/2024 - 11/2008
22Indicators and Reagents (Reagents)IBA
11/2023 - 05/2004
22Small Interfering RNA (siRNA)IBA
01/2022 - 01/2006
21Peptides (Polypeptides)IBA
03/2024 - 08/2005
18Apolipoproteins E (ApoE)IBA
11/2024 - 01/2013
18Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2022 - 01/2005
17Blood Glucose (Blood Sugar)IBA
05/2024 - 05/2017
17LigandsIBA
05/2024 - 02/2015
16AntigensIBA
11/2023 - 04/2005
15Transcription Factors (Transcription Factor)IBA
02/2024 - 09/2008
14Interleukin-6 (Interleukin 6)IBA
03/2024 - 08/2005
13Circular RNAIBA
01/2024 - 08/2016
13DNA (Deoxyribonucleic Acid)IBA
12/2023 - 03/2007
12VaccinesIBA
03/2024 - 02/2012
12LipopolysaccharidesIBA
02/2024 - 02/2016
12CateninsIBA
11/2023 - 09/2012
12Neuroprotective AgentsIBA
11/2023 - 03/2012
12CollagenIBA
09/2023 - 02/2015
12Retinaldehyde (Retinal)IBA
01/2023 - 01/2012
11Phosphotransferases (Kinase)IBA
03/2024 - 01/2012
11AntioxidantsIBA
03/2024 - 10/2012
11Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2023 - 02/2007
11Immune Checkpoint InhibitorsIBA
08/2023 - 01/2021
11p38 Mitogen-Activated Protein KinasesIBA
05/2023 - 09/2007
10Triglycerides (Triacylglycerol)IBA
05/2024 - 01/2016
10Chimeric Antigen ReceptorsIBA
02/2024 - 01/2021
10Anti-Bacterial Agents (Antibiotics)IBA
02/2024 - 12/2014
10Antiviral Agents (Antivirals)IBA
02/2024 - 03/2015

Therapy/Procedure

187Therapeutics
05/2024 - 08/2005
53Drug Therapy (Chemotherapy)
02/2024 - 11/2005
40Immunotherapy
01/2024 - 04/2005
20Chinese Traditional Medicine (Traditional Chinese Medicine)
03/2024 - 01/2018
20Radiotherapy
01/2023 - 06/2015
15Thrombectomy
10/2023 - 06/2016
12Transplantation
11/2023 - 04/2014
10Castration
02/2024 - 12/2017